Gender differences in ischemic heart disease among Middle-Eastern population

Background/Aim. In the past three decades, focal segmental glomerulosclerosis (FSGS) was commonly regarded as a part of obesity-related glomerulopathy (ORG), distinct entity featuring proteinuria, glomerulomegaly, progressive glomerulosclerosis, and decline renal function. The present study aimed to evaluate glomerular morphometry, clinical features, two-year outcome in obese non-obese FSGS patients. Methods. included 35 patients (23 males, aged 46.5 ? 15.2 years) divided into two groups: [body mass index (BMI) 27 kg/m2 (18 patients, 47.2 15.5 years)] [BMI < (17 45.7 years)]. serum concentrations proteins, albumin, cholesterol, tri-glyceride, creatinine were determined at time biopsy, 6, 12, 24 months after biopsy. Cock-croft-Gault (BMI kg/m2) Cockcroft-GaultLBW formulas calculated. Glomerular radius (GR), volume (GV), density (GD) compared morphometrically between groups. Results. At kidney biopsy 6 later, had significantly lower filtration rate (GFR) non-obese. After follow-up, there not any differences higher GR (109.44 6.03 ?m vs. 98.53 14.38 ?m) GV (3.13 0.49 106 ?m3 2.26 0.83 ?m3), only slightly GD (1.91 0.39/mm2 1.95 0.61/mm2) A significant positive association BMI (r = 0.439) found. 12 percentage reached complete remission (71.4% 37.5%, respectively; p 0.041), but no differences. Conclusion. Obese already function ones. However, after, this difference statistically significant. Also, groups with nephrotic syndrome.